Plain-English translation of NCT05309746 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether removing and freezing ovarian tissue before cancer treatment can help preserve a young person's ability to have children in the future. The frozen tissue would be stored and potentially used later when new fertility restoration techniques become available. Researchers will also study the tissue to find better ways to freeze and preserve it.
Many cancer treatments like chemotherapy and radiation damage or destroy the ovaries, making it impossible for young women to become pregnant naturally later in life. This study exists to offer a way to preserve fertility before these treatments happen, giving patients hope for biological children in the future.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will have a minor surgical procedure called laparoscopy (done while you're asleep) to remove a small piece of one ovary before your cancer treatment begins. The tissue will be frozen using a special process to preserve it for possible future use. You'll also be asked to donate a tiny sample of tissue for research to help improve freezing techniques. After surgery, you'll complete yearly surveys to track your health and the long-term effects of the procedure.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
United States
Sponsor
Erin Rowell
Enrollment target
~250 participants
Started
November 2017
Primary completion
December 2030
Sex
Female only
Last updated on clinicaltrials.gov in September 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Sara Reyes
Lurie Childrens Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.