Plain-English translation of NCT05323864 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how your body and mood respond when oxygen levels drop, similar to being at high altitude (around 12,500 feet). This study compares how people with anxiety or depression symptoms react to low-oxygen conditions versus normal conditions in a safe laboratory chamber. The findings may help doctors give better advice to people with mental health conditions who want to hike or travel to mountains.
Millions of people with mental health conditions visit high-altitude areas like the Alps each year, but doctors don't have clear guidelines about whether it's safe for them. This research will help fill that gap by studying how low oxygen affects mood, anxiety, and brain chemistry in people with mental illnesses.
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You will visit the laboratory twice for separate six-hour sessions in a sealed chamber. During one visit, the oxygen level will be lowered to simulate being at 12,500 feet altitude; during the other visit (as a control), oxygen will stay normal—but you won't know which is which. Before, during, and after each session, researchers will ask you about your mood and anxiety using simple questionnaires, and they'll take blood samples to measure stress markers and other biological changes.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
Austria