Plain-English translation of NCT05325099 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether a medication called can help prevent acute kidney injury from developing into long-term kidney disease. Researchers believe this medication may work by reversing harmful changes in kidney cells that occur after heart surgery. The study will compare patients who receive the medication with those who receive a placebo (an inactive treatment) to see if it makes a difference.
Right now, doctors have no proven medications to treat acute kidney injury or prevent it from becoming chronic kidney disease. Most patients only receive supportive care and monitoring. This trial exists because early research suggests this medication might actually prevent the progression of kidney damage—which would be a major breakthrough.
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You would be randomly assigned to receive either the medication or a placebo, both given as injections under the skin. The trial will monitor your kidney function and overall health over time to see whether the medication helps prevent your kidney injury from becoming a long-term problem. You'll have blood tests and follow-up visits to track how your kidneys are recovering.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
Taiwan
Sponsor
National Taiwan University Hospital
Enrollment target
~60 participants
Started
April 2024
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
20 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Yu Hsiang Chou, PhD
National Taiwan University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.