Plain-English translation of NCT05326295 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Neoplasms research guide →This is an observational study that follows breast cancer patients receiving chemotherapy before or after surgery. Researchers will monitor circulating tumor cells — cancer cells that have entered the bloodstream — by taking blood samples at different points during your treatment. The goal is to understand whether tracking these cells can help predict how well your chemotherapy is working and whether cancer might return.
Currently, doctors must wait weeks or months after chemotherapy to see if tumors have shrunk on imaging scans. This study aims to find an earlier warning signal — by monitoring cancer cells in the blood — so doctors can know sooner whether the treatment is effective and adjust the plan if needed.
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You will receive your standard breast cancer chemotherapy and surgery as planned by your oncologist — the study does not change your treatment. In addition, you will have blood drawn at several time points: before chemotherapy starts, during treatment, after chemotherapy ends, and during follow-up visits. These blood samples will be analyzed to track circulating tumor cells and measure certain markers on their surface. The study follows you for as long as medically appropriate to monitor whether cancer returns.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
China
Sponsor
Hunan Cancer Hospital
Enrollment target
~1,000 participants
Started
March 2019
Primary completion
March 2028
Age range
18 Years – 75 Years
Sex
Female only
Last updated on clinicaltrials.gov in April 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Quchang Ouyang
Hunan Cancer Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.