Plain-English translation of NCT05326295 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Neoplasms research guide →This is an observational study that follows breast cancer patients receiving chemotherapy before or after surgery. Researchers will monitor circulating tumor cells — cancer cells that have entered the bloodstream — by taking blood samples at different points during your treatment. The goal is to understand whether tracking these cells can help predict how well your chemotherapy is working and whether cancer might return.
Currently, doctors must wait weeks or months after chemotherapy to see if tumors have shrunk on imaging scans. This study aims to find an earlier warning signal — by monitoring cancer cells in the blood — so doctors can know sooner whether the treatment is effective and adjust the plan if needed.
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You will receive your standard breast cancer chemotherapy and surgery as planned by your oncologist — the study does not change your treatment. In addition, you will have blood drawn at several time points: before chemotherapy starts, during treatment, after chemotherapy ends, and during follow-up visits. These blood samples will be analyzed to track circulating tumor cells and measure certain markers on their surface. The study follows you for as long as medically appropriate to monitor whether cancer returns.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
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