Plain-English translation of NCT05326477 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is investigating why people from lower-income backgrounds often lose less weight in standard weight loss programs compared to those from higher-income backgrounds. Researchers will enroll 230 people—equally from lower and higher income groups—in a 6-month group-based weight loss program. The study will carefully track weight loss, eating habits, physical activity, and daily stressors to understand what factors might explain these differences.
Studies have shown that people from lower-income backgrounds typically lose only about half as much weight in weight loss programs as those from higher-income backgrounds. This research aims to identify the reasons behind this disparity—such as stress, daily challenges, or how people think about immediate versus long-term needs—so that future weight loss treatments can be redesigned to work better for everyone, regardless of income.
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You will attend a 6-month group-based weight loss program that follows a standard, evidence-based curriculum. During this time, you'll meet regularly with the group, track your eating and physical activity, and complete assessments about your daily experiences and stress levels. Researchers will also use your cell phone to check in with you at random moments throughout the day to understand your real-world eating triggers and stressors, and you'll have follow-up visits to measure your weight and progress.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States
Sponsor
Rush University Medical Center
Enrollment target
~230 participants
Started
May 2023
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Bradley M Appelhans, PHD
Rush University Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.