Plain-English translation of NCT05330910 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Sleeve gastrectomy is a common weight loss surgery that makes the stomach smaller. However, it can sometimes cause acid reflux (heartburn) afterward. This study is testing whether fixing a hiatal hernia—a weakness in the muscle that holds the stomach in place—at the same time as the weight loss surgery can prevent acid reflux from developing. About 96 people will be randomly assigned to either have the weight loss surgery alone or the weight loss surgery combined with hernia repair.
Acid reflux is a common problem after weight loss surgery, and it can damage the food pipe. Doctors think that repairing a weak valve or hernia at the time of surgery might prevent this problem, but no one has studied this carefully in the right way yet.
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You will have a preoperative endoscopy (camera test of your stomach) to confirm you are eligible. Then you will undergo sleeve gastrectomy surgery performed by the study team using a standardized technique. Half of participants will also have hernia repair done during the same surgery. After surgery, you will follow a standard recovery plan with liquids and vitamins for the first two weeks, then gradually return to solid foods. The study team will monitor you and assess your symptoms over time to see if adding hernia repair reduces acid reflux.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
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