Plain-English translation of NCT05332639 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new online tool called PRE-Crohn's that gives personalized risk information to people who don't have Crohn's disease yet but are at higher risk because a close family member has it. The tool is designed to help you understand your personal risk and make lifestyle and dietary changes that might prevent the disease from developing. Researchers will compare how well this personalized tool works compared to standard educational materials about Crohn's disease.
Many people have a family member with Crohn's disease, which puts them at higher risk of developing it themselves. Right now, there aren't proven ways to prevent Crohn's disease in people at high risk. This study is testing whether giving people personalized risk information and helping them make healthy lifestyle changes could prevent the disease from developing in the first place.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly assigned to either use the new PRE-Crohn's online tool or receive standard educational information about Crohn's disease. You will attend multiple study visits at Massachusetts General Hospital where researchers will collect health information, ask you questions about your diet and lifestyle, and take blood samples to look for early signs of disease. The study will track how your behaviors and health markers change over time to see if the personalized tool helps prevent Crohn's disease better than standard education.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States