Plain-English translation of NCT05340062 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
When a child's brain swells, doctors need to measure the pressure inside the skull to prevent serious damage. This trial is testing whether two ultrasound-based methods—transcranial Doppler (which measures blood flow in brain vessels) and optic nerve sheath measurement (which looks at the nerve behind the eye)—can accurately measure brain pressure without needing invasive catheters. These ultrasound methods are safer because they avoid surgery and the risks of bleeding or infection.
Currently, the most reliable way to measure brain pressure requires surgeons to place catheters inside the brain, which carries risks of complications. Doctors need non-invasive alternatives that are faster, safer, and just as accurate—especially for children.
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If you are enrolled, doctors will perform two types of ultrasound scans—one before your invasive monitoring device is placed (if possible) and at least twice daily for the first 48 hours after placement. Each scan takes just a few minutes and involves a technician moving an ultrasound probe over your temple and eye area. Your regular brain pressure readings will be compared to the ultrasound measurements to see how accurate the non-invasive methods are.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
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