Plain-English translation of NCT05340647 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
NorMIGS is a research study testing whether a newer, less invasive surgical device called the Preserflo microshunt can effectively lower eye pressure in people with glaucoma. Researchers will compare how well the Preserflo microshunt works compared to two other surgical approaches: traditional trabeculectomy surgery and other newer micro-invasive glaucoma procedures. The study will track how much eye pressure drops and whether any complications occur after each type of surgery.
Glaucoma damages the eye's optic nerve and can cause blindness if eye pressure isn't controlled. Doctors have several surgical options, but newer, less invasive techniques like the Preserflo microshunt may offer benefits over traditional surgery. This study will help determine which surgical approach works best and is safest for patients.
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You will receive one of the three surgical treatments at Oslo University Hospital and then attend follow-up visits so researchers can measure your eye pressure and check for any complications. The study will track how well your eye pressure is controlled after surgery and monitor you for side effects. Your specific schedule will depend on which surgical approach you receive, but you should be prepared for multiple office visits over time to allow doctors to assess how you're healing and how well the surgery is working.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Norway
Sponsor
Oslo University Hospital
Enrollment target
~100 participants
Started
April 2022
Primary completion
December 2023
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Olav Kristianslund, MD PhD
Department of Ophthalmology, Oslo University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.