Plain-English translation of NCT05344651 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing whether a newer glaucoma drainage device called the Paul implant causes less damage to the cornea (the clear front part of your eye) than an older device called the Baerveldt implant. Both devices are surgical implants designed to lower eye pressure and slow glaucoma progression. The study will follow patients for two years to compare how well each implant works and how it affects the health of corneal cells.
While the Baerveldt implant successfully lowers eye pressure, doctors have noticed it can sometimes damage the delicate cells lining the front of the eye over time. The Paul implant has a thinner tube design that may sit farther away from these cells, potentially causing less harm.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
You will undergo surgery to receive one of the two glaucoma implants (randomly assigned). After surgery, you will visit the clinic about 5 times over two years for follow-up eye exams, taking about 1.5 hours per visit. These visits will measure your eye pressure, check how your cornea is doing, and confirm the position of the implant. The total time commitment is approximately 7.5 hours spread across two years.
AI-generated summary from trial data ยท Jun 6, 2026 ยท Not medical advice
Netherlands