Plain-English translation of NCT05346068 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a newer technique called Shockwave Intravascular Lithotripsy (IVL) — which uses sound waves to break up calcium deposits in heart arteries — works as well as a traditional high-pressure balloon for treating severely calcified coronary artery blockages. If you join, you'll be randomly assigned to receive one of these two preparation methods before your doctor places a stent to open the blocked artery.
When calcium builds up in coronary arteries, it becomes very difficult to open the blockage safely and effectively with standard balloons. This trial aims to find out whether the newer sound-wave technique is a reliable alternative to the high-pressure balloon approach.
You likely qualify if…
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You will be randomly assigned to receive either the Shockwave IVL catheter or a super high-pressure balloon to prepare your calcified artery blockage, followed by stent placement. Your doctor will use special imaging (OCT) to guide the procedure and check the results. You'll have follow-up visits at 30 days, 1 year, and 2 years after the procedure to monitor your recovery and heart health.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
Switzerland