Plain-English translation of NCT05346367 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether spreading stereotactic radiotherapy (a focused radiation treatment) over five separate appointments works better than delivering it in just one or three appointments. Researchers want to see if the longer schedule reduces brain damage from radiation while still controlling the cancer effectively.
Although stereotactic radiotherapy works well against brain tumors, about 40% of patients develop brain damage from the radiation over time. Early studies suggest that spreading the treatment over more sessions might reduce this serious side effect, especially for larger tumors.
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You will be randomly assigned to receive either focused radiation in one or three sessions, or five shorter sessions over a longer period. You'll have MRI scans and check-ins to monitor how well the treatment is working, any side effects you experience, and how the treatment affects your quality of life. The study will track your health outcomes over time.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Netherlands