Plain-English translation of NCT05348564 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This study doesn't follow the usual testing phases โ it may be an observational study or a different type of research.
This trial is testing the best way to reach family members of people who carry a genetic mutation for Long QT Syndrome or Familial Hypercholesterolemia โ two inherited conditions that affect the heart and cholesterol levels. The study compares two approaches: one where you tell your relatives about screening yourself, and another where the study team contacts them directly. All interested family members will receive free genetic testing and counseling.
These genetic conditions run in families, and early identification can help prevent serious health problems. This research wants to find out whether it's more effective when family members hear about screening from their relatives directly, or when the study team reaches out to them.
You likely qualify ifโฆ
You likely don't qualify ifโฆ
If you are a carrier (called a 'proband'), you will be randomly assigned to either contact your relatives yourself or allow the study team to contact them on your behalf. You will meet with the research team once to discuss the study and receive educational materials. Your relatives who are interested will be offered free saliva-based genetic testing done at home, along with genetic counseling before and after testing. The study team will follow up with family members over about two weeks to encourage participation.
AI-generated summary from trial data ยท Sep 24, 2026 ยท Not medical advice
United States