Plain-English translation of NCT05349955 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 2 Diabetes research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a guideline-based approach to treating older adults with type 2 diabetes—including newer medications like SGLT2 inhibitors and GLP-1 receptor agonists—can better protect the heart and kidneys than standard care. The study will follow over 5,600 patients aged 65 and older across 120 community health centers to see if this intensive medication strategy reduces serious heart events and kidney problems over 4 years.
Many older adults with diabetes also have heart disease or kidney damage, which puts them at high risk for heart attacks and strokes. Newer medications have shown promise in protecting the heart and kidneys, but doctors in community clinics don't always use them. This trial will test whether teaching primary care doctors to follow updated guidelines and use these protective medications can prevent serious complications.
You likely qualify if…
You likely don't qualify if…
You will be assigned to one of two groups: either intensive guideline-based treatment with newer medications designed to protect your heart and kidneys, or your doctor's usual approach with some guideline education. Your doctor will monitor your blood sugar, blood pressure, and cholesterol levels at clinic visits over 4 years, with formal check-ins at 18 months and 3 years to measure how well the treatment is working and whether it reduces serious heart and kidney problems.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
China