Plain-English translation of NCT05350332 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is exploring how lung volume affects the airway during a procedure called drug-induced sleep endoscopy (DISE), which doctors use to evaluate sleep apnea patients for surgery. During DISE, a thin camera is placed through your nose to visualize how your airway collapses during sedation. This study will test two methods to increase your lung volume during the procedure — using a negative pressure ventilator or phrenic nerve stimulation — to see if this helps doctors better understand your airway and predict which surgical treatments will work best for you.
Many people with sleep apnea don't tolerate the standard treatment (a pressurized mask), and while surgery can help, the success rate varies widely depending on the patient. By better understanding how lung volume affects airway collapse, doctors hope to improve their ability to select the right patients for surgery and develop new treatment options for those who don't respond to current therapies.
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You will be enrolled as part of your routine clinical evaluation for sleep apnea surgery. During your scheduled DISE procedure, researchers will use either a negative pressure ventilator or phrenic nerve stimulation to increase your lung volume while the camera visualizes your airway. You will also complete a pulmonary function test (breathing test) for research purposes. The study involves no additional visits beyond your standard clinical care, though the testing will take extra time during your scheduled procedure.
AI-generated summary from trial data · Sep 4, 2026 · Not medical advice
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