Plain-English translation of NCT05353452 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial studied a new way of delivering mental health care to people with epilepsy that developed after a traumatic brain injury and who were also experiencing anxiety or depression. Instead of seeing different doctors separately, participants in the collaborative care group worked with a coordinated team of neurologists, mental health specialists, and care coordinators who communicated with each other and worked together over 24 weeks. The study compared this team-based approach to the standard care that people typically receive.
Many people with epilepsy after brain injury struggle with anxiety and depression, and treating these conditions alongside epilepsy can be complicated when different doctors don't communicate. This trial tested whether having a coordinated team focused on all three conditions together — rather than managing them separately — would help people feel better.
Participants received either the new collaborative care approach or standard care for 24 weeks. Those in the collaborative care group worked with a team that included neurologists and mental health specialists who coordinated treatment for both their epilepsy and anxiety or depression symptoms, with many visits delivered remotely. All participants completed questionnaires about their symptoms and mood at different time points throughout the study.
AI-generated summary from trial data · Aug 3, 2026 · Not medical advice
United States
Sponsor
Wake Forest University Health Sciences
Enrollment target
~40 participants
Started
April 2023
Primary completion
May 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.