Plain-English translation of NCT05356611 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a therapy program called Engage, designed specifically for older adults who have depression along with mild thinking and memory problems. The program involves nine weeks of structured sessions that adapt traditional therapy to work better for people experiencing cognitive decline. Researchers want to see if Engage is a practical and effective way to treat depression in older adults whose memory or thinking challenges might make standard therapy harder to follow.
Many older adults experience both depression and cognitive decline at the same time, but most depression treatments weren't designed with memory or thinking problems in mind. This trial exists to fill that gap by testing whether this adapted treatment can work for people facing both challenges together.
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You would attend therapy sessions over a period of nine weeks, visiting the University of Nevada, Las Vegas campus regularly. During these sessions, a therapist would lead you through the Engage program, which uses strategies specifically adapted to help people with both depression and cognitive challenges. The program focuses on behavioral approaches—practical strategies and activities—to help improve your mood and functioning in everyday life.
AI-generated summary from trial data · Jun 23, 2026 · Not medical advice
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