Plain-English translation of NCT05364125 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a simple smell training program can help restore your ability to smell. You would use special diffusers with aromatic substances several times a day for three months. The study compares people who receive real aromatic training to those who receive a placebo (a non-active version), so researchers can see if the smell training truly works.
Losing your sense of smell can significantly affect your quality of life and ability to enjoy food and stay safe. This medication-free approach offers a potential non-invasive way to help people regain or improve their sense of smell, which currently has limited treatment options.
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You would start with smell and taste tests to measure your baseline ability. Then you'd be randomly assigned to either the active treatment group or the control group. Three times daily for 3 months, you would use a diffuser for 80 seconds total (four 20-second sessions). At the end, you would repeat the initial tests to see if your sense of smell improved. The entire study runs from July 2022 through June 2024.
AI-generated summary from trial data · Aug 20, 2026 · Not medical advice
Hong Kong
Sponsor
Pamela Youde Nethersole Eastern Hospital
Enrollment target
~80 participants
Started
July 2022
Primary completion
June 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kai Chuen Fergus Wong, FRCSEd(ORL)
Pamela Youde Nethersole Eastern Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.