Plain-English translation of NCT05365425 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether , a medication that helps manage cholesterol and triglycerides, can slow down the buildup of plaque and thickening in your carotid arteries (the major blood vessels in your neck that supply blood to your brain). You'll be compared to people taking a different cholesterol-supporting medication called to see which works better at protecting your arteries. The study uses ultrasound imaging to measure changes in your artery walls over time.
People with type 2 diabetes and high triglycerides combined with low 'good' cholesterol face a higher risk of heart attack and stroke because plaque builds up in their arteries. This medication has been used to treat cholesterol for years, but doctors want to confirm that it actually slows down artery damage in this specific group of patients.
You likely qualify if…
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You will take one tablet by mouth once daily—either the or the —for the study period. At visits, you'll have blood tests to check your cholesterol and kidney function, and a special 3D ultrasound of your neck arteries to measure any changes in plaque and artery wall thickness. The study tracks whether your arteries are getting worse or staying stable, helping doctors understand if this medication truly protects your blood vessels.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
South Korea
Phase
Post-approval monitoring
Sponsor
Seoul National University Bundang Hospital
Collaborators
Daewon Pharmaceutical Co., Ltd.
Enrollment target
~56 participants
Started
June 2023
Primary completion
December 2026
Age range
20 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Soo Lim
Seoul National University Bundang Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.