Plain-English translation of NCT05368974 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hepatitis C research guide →This study is tracking pregnancies and baby health outcomes in women with hepatitis C who received direct-acting antiviral (DAA) medications—a newer type of hepatitis C treatment—during or shortly before pregnancy. Researchers want to understand whether treating hepatitis C during pregnancy is safe for both mother and baby, and whether it might reduce the chance of passing the infection to the newborn.
For years, women with hepatitis C during pregnancy couldn't safely receive treatment because older medications could harm the developing baby. The newer antiviral medications appear safer to use in pregnancy, and many women say they would want treatment if it could protect their baby from infection. However, doctors don't yet have clear information about how safe and effective this approach really is, so this registry is collecting real-world data to answer that question.
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This is an observational registry, not an experimental treatment study—you won't receive any new medication as part of joining. Instead, researchers will collect and review your medical records, including information about your hepatitis C diagnosis, the medication you received, your pregnancy course, and your baby's health after birth. Data collection happens over time as your pregnancy progresses and after delivery.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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