Plain-English translation of NCT05371977 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different surgical approaches to treat normal tension glaucoma — a condition where the eye's drainage system doesn't work well, even though eye pressure remains normal. Researchers want to compare deep sclerectomy and trabeculectomy to see which surgery works better at stabilizing the disease and protecting your vision over time.
Normal tension glaucoma can continue to damage vision even when eye pressure stays in the normal range and medications are being used. Surgery may help, but doctors aren't certain which surgical approach is most effective for this specific type of glaucoma, so this trial will help answer that question.
You likely qualify if…
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If you join this study, you will be randomly assigned to receive one of the two surgical treatments — either deep sclerectomy or trabeculectomy. Both are outpatient procedures performed by eye surgeons. After surgery, you will have follow-up visits to monitor how well the surgery worked and whether your glaucoma remains stable. The study will track your eye pressure, vision, and optic nerve health over time to compare how the two approaches perform.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Finland
Sponsor
Helsinki University Central Hospital
Enrollment target
~80 participants
Started
May 2022
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
55 Years – 100 Years
Last updated on clinicaltrials.gov in March 2024.
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