Plain-English translation of NCT05372159 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Alzheimer Disease research guide →Researchers at Vanderbilt are studying how your heart's health may affect your brain as you age. The study involves adults ages 50 and older—some with normal memory and thinking skills, and some with early mild memory problems. By measuring your heart function and taking detailed brain images, the team hopes to understand why some people develop memory loss and whether heart changes might be an early warning sign.
As people age, Alzheimer's disease and dementia are becoming more common health problems. Early research suggests that subtle changes in how the heart pumps blood may contribute to brain aging and memory loss, even before someone notices any problems. This trial aims to find these early warning signs so doctors might one day prevent or slow cognitive decline.
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You will start with a 4-hour screening visit where doctors will test your memory and thinking skills and review your medical history. If you qualify, you'll have follow-up visits that include heart function tests and an MRI scan of your brain. You will also need a study partner (family member or close friend) who can help track any changes over time. The study is designed to follow participants over multiple visits to see how heart and brain health change together.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
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