Plain-English translation of NCT05372172 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The Tennessee Alzheimer's Project is a long-term research study that follows people ages 60 and older to understand how Alzheimer's disease develops, progresses, and affects the brain. Researchers will use memory tests, brain imaging, blood tests, and other evaluations to learn more about the disease in people with normal cognition, mild memory problems, and Alzheimer's disease. This information could help develop better prevention strategies and treatments for millions of Americans affected by this disease.
Alzheimer's disease affects nearly 6 million Americans and is expected to become even more common as the population ages. We don't fully understand how the disease starts and progresses, or why some treatments work better for certain people—so this study aims to fill those gaps and help researchers develop more effective ways to prevent and treat the disease.
You likely qualify if…
You likely don't qualify if…
You would visit the research center annually for comprehensive evaluations including memory and thinking tests, physical exams, blood draws, brain imaging (MRI), heart imaging (echocardiogram), and possibly a spinal fluid sample. You'll also complete questionnaires about your health and daily life. The study team may ask you to consider donating your brain and other tissues after death to help researchers better understand the disease. All participants are assigned to a group based on their current cognitive status, and you'll be followed over time to see how thinking and memory change.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States