Plain-English translation of NCT05376046 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →This research study is looking at blood test results from people with sickle cell disease to see if certain markers in the blood can help predict when a vaso-occlusive crisis (a painful complication) might occur. Researchers will compare blood samples from people with sickle cell disease to healthy volunteers to understand what patterns might warn of a coming crisis.
Sickle cell disease causes painful crises that send many people to the hospital. If doctors could predict when these crises are about to happen using simple blood tests, they might be able to prevent them or help patients prepare. This study aims to find those warning signs in routine lab work.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will have blood samples taken during a visit to the medical center. Researchers will analyze your blood using standard laboratory tests to measure different markers related to hemolysis (red blood cell breakdown). The study compares results from people with sickle cell disease to healthy volunteers matched by age and gender to identify patterns that might predict crises.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
France
BILLOIR
Enrollment target
~200 participants
Started
September 2018
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2022.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.