Plain-English translation of NCT05376254 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This research study is testing whether three-dimensional ultrasound imaging of your heart can help doctors predict which patients receiving a left ventricular assist device (LVAD) — a mechanical pump that helps a failing heart pump blood — might develop problems with their right heart chamber after surgery. Currently, doctors use older two-dimensional imaging that may not show the complete picture. This study will examine detailed 3D images taken during your LVAD implantation surgery to see if they can better predict complications.
Right heart failure happens in roughly 1 out of 4 to 1 out of 2 patients who receive a heart pump, and it can lead to serious complications. Better imaging tools could help doctors identify at-risk patients earlier and potentially prevent these problems from developing.
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You would be participating in this study as part of your scheduled left ventricular assist device implantation surgery. During your procedure, doctors will obtain three-dimensional ultrasound images of your right heart chamber and collect information about your heart's function. Researchers will then analyze these images to see if they can predict which patients develop right heart problems in the two weeks following surgery. There are no additional visits or procedures required beyond your standard surgical care.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
Canada
Sponsor
University of Alberta
Enrollment target
~200 participants
Started
March 2022
Primary completion
January 2027
Age range
16 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Surita Sidhu, MD
University of Alberta
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.