Plain-English translation of NCT05377125 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a computerized training program designed to help people with obsessive-compulsive disorder (OCD), trichotillomania (hair-pulling), or skin-picking disorder. The program works like a 40-level computer game that helps you practice stopping automatic thoughts and responses. Researchers believe that strengthening this ability to inhibit or 'stop' unwanted responses may reduce OCD and related symptoms, and they'll use brain scans to see if the training actually changes how your brain works.
People with OCD and related conditions often struggle with a specific brain function called response inhibition—the ability to stop automatic or unwanted thoughts and behaviors. No existing treatment directly targets this problem, so researchers developed this training program to fill that gap and potentially make treatment more effective.
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You would be randomly assigned to either the response inhibition training program or a placebo control training. If you receive the real training, you'll attend 8 to 16 sessions (each lasting about 45 minutes) where you'll play a computer game designed to improve your ability to stop unwanted responses. Researchers will measure your progress using a reaction-time task and brain imaging before and after training, and they'll follow up with you one month later to see if your OCD or related symptoms have improved.
AI-generated summary from trial data · Jul 14, 2026 · Not medical advice
United States