Plain-English translation of NCT05378490 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The ASIST-1 study is tracking thousands of patients who arrive at a Norwegian hospital with stroke symptoms to understand how doctors decide which patients need emergency treatment, how well different treatments work, and what helps patients recover. Researchers are studying emergency clot-busting medications, procedures to remove blood clots from the brain, and care for bleeding in the brain. The goal is to learn what works best and why some patients recover better than others.
Stroke is a medical emergency where minutes matter, but doctors don't always agree on who should receive emergency treatment or which treatment is best. This study wants to understand real-world stroke care and outcomes so hospitals can improve how quickly and effectively they treat patients.
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If you join, researchers will review your medical records, imaging scans, and test results from your hospital visit. You'll be followed for up to 5 years, with researchers checking on your recovery and outcomes at discharge, 3 months, 1 year, and 2 years. Most of this happens through your medical records — you're not required to come back for extra visits beyond your regular stroke care.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
Norway
University of Oslo, Oslo University Hospital
Enrollment target
~6,000 participants
Started
January 2012
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Espen S. Kristoffersen, MD, PhD
University Hospital, Akershus
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.