Phase 1 — Early testing in a small group of people (usually 20–80) to evaluate safety, determine safe dosage, and identify side effects.
(53 sites) United States
O Neal Comprehensive Cancer Center at UAB, Birmingham, Alabama University of Southern California, Los Angeles, California University of California, Los Angeles UCLA, Los Angeles, California Georgetown University Hospital, Washington D.C., District of Columbia H Lee Moffitt Cancer Center, Tampa, Florida University of Maryland School of Medicine, Baltimore, Maryland University of Michigan Health System, Ann Arbor, Michigan Start Midwest, Grand Rapids, Michigan Hattiesburg Clinic, Hattiesburg, Mississippi NYU Langone Long Island Clinical Research Associates, New York, New York Herbert Irving Comprehensive Cancer Center Columbia University Medical Center, New York, New York Stephenson Cancer Center, Oklahoma City, Oklahoma Vanderbilt Ingram Cancer Center, Nashville, Tennessee MD Anderson Cancer Center, Houston, Texas Belgium
Institut Jules Bordet, Anderlecht Cliniques Universitaires Saint Luc, Brussels Universitair Ziekenhuis Gasthuisberg, Leuven Canada
BC Cancer Agency - Vancouver BC, Vancouver, British Columbia The Ottawa Hospital Cancer Centre, Ottawa, Ontario Princess Margaret Cancer Centre University Health Network, Toronto, Ontario China
The Second Hospital To Dalian Medical University, Dalian Sun Yat-sen University - The Sixth Affiliated Hospital Guangdong Gastrointestinal Hospital, Guangzhou The Second Affiliated Hospital of Zhejiang University College of Medicine, Hangzhou Hubei province tumor hospital, Wuhan Germany
Asklepios Klinik Altona, Hamburg Ludwig-Maximilians-Universitaet Muenchen, Munich Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan A O Ospedale Niguarda Ca Granda, Milan Azienda Ospedaliero Universitaria Pisana, Pisa Malaysia
University Malaya Medical Centre, Kuala Lumpur Hospital Umum Sarawak, Kuching Beacon Hospital Sdn Bhd, Petaling Jaya Puerto Rico
Ad Vance Medical Research, Ponce Pan American Center for Oncology Trials LLC, Rio Piedras South Korea
Seoul National University Hospital, Seoul Severance Hospital Yonsei University Health System, Seoul Asan Medical Center, Seoul Samsung Medical Center, Seoul The Catholic University of Korea Seoul St Mary s Hospital, Seoul Spain
Hosp Univ Vall D Hebron, Barcelona Hosp. Gral. Univ. Gregorio Maranon, Madrid Hosp. Univ. Ramon Y Cajal, Madrid Hosp Univ Fund Jimenez Diaz, Madrid Hosp Univ Hm Sanchinarro, Madrid Hosp. Univ. Marques de Valdecilla, Santander Hosp. Clinico Univ. de Valencia, Valencia Taiwan
Changhua Christian Hospital, Changhua Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City Chi Mei Medical Center Liu Ying, Liou Ying Township National Cheng Kung University Hospital, Tainan National Taiwan University Hospital, Taipei Linkou Chang Gung Memorial Hospital, Taoyuan District