Plain-English translation of NCT05385237 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new MRI scanning technique called 4D-MRI to detect liver scarring (fibrosis) in people with chronic liver diseases. Unlike current methods, this scan captures detailed images of how your liver moves and stretches during breathing, allowing doctors to measure liver stiffness without need for a biopsy or other invasive procedures. The scan uses no radiation and could help doctors better understand how advanced your liver disease is.
Liver scarring is a serious problem that can develop slowly in people with chronic liver disease, eventually leading to liver failure or cancer. Currently, doctors struggle to accurately measure scarring without doing a liver biopsy (taking a small tissue sample), which is invasive and uncomfortable. This trial exists to see if the new scanning technique can safely and accurately detect scarring earlier, so doctors can better monitor disease progression and test new treatments.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will come for an MRI appointment where you'll lie in an MRI scanner while it takes detailed images of your liver over several minutes. During the scan, you'll breathe normally—the machine captures how your liver moves with each breath. The scan itself is painless and uses no radiation. The visit will likely take about 1–2 hours total, including preparation and the scanning time.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Switzerland