Plain-English translation of NCT05386173 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is following families who have a baby diagnosed with aortic valve stenosis—a condition where the heart valve that controls blood flow is too narrow. The study compares two groups: babies whose families choose to have a fetal balloon dilation procedure (a minimally invasive treatment done before birth) and babies whose families do not have this procedure. Researchers want to understand how this early treatment affects the baby's heart development and long-term health outcomes.
Aortic valve stenosis can affect how the left side of the heart develops during pregnancy, and in severe cases the heart may not grow enough to work properly after birth. This study exists to find out whether treating the narrowed valve before birth helps the left heart structures grow better and improves outcomes for babies after they are born.
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If you enroll, you and your baby will have routine heart ultrasounds (echocardiograms) during pregnancy and after birth—the same imaging your doctor would recommend whether or not you join the study. Your medical information and ultrasound images will be entered into a secure database for researchers to analyze. The study does not change the number of visits or tests you receive, and your regular care before and after birth continues as planned; the study simply collects and compares data between families who choose the early procedure and those who do not.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
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