Plain-English translation of NCT05390515 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers want to understand exactly how tildrakizumab works to treat psoriasis by studying immune cells in your skin and blood. You would receive the medication as part of your regular treatment, and researchers would take small skin samples and blood samples before and during your treatment to analyze how the immune system responds.
While this medication is already approved and used to treat psoriasis, doctors don't yet fully understand all the ways it works at a cellular level. This study will help researchers learn more about how the treatment changes your immune system, which could lead to better psoriasis treatments in the future.
You likely qualify if…
You likely don't qualify if…
You will receive tildrakizumab as your psoriasis treatment. Before you start and at certain points during treatment, you will have clinic visits where doctors will take a small skin sample (biopsy) from an affected area and draw blood samples. These samples will be analyzed in the laboratory to study how your immune cells change in response to the medication. The study involves a small group of 10 people, so visits may be relatively straightforward.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States
Sponsor
University of California, San Francisco
Collaborators
Sun Pharmaceutical Industries Limited
Enrollment target
~10 participants
Started
September 2022
Primary completion
September 2028
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Raymond Cho, MD, PhD
University of California, San Francisco
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.