Plain-English translation of NCT05397262 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Bladder Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a combination treatment for bladder cancer that uses deep regional hyperthermia (controlled heating of the bladder area) paired with radiation therapy and, for some patients, chemotherapy drugs including 5-Fluorouracil and Cisplatin. The goal is to see whether adding heat to radiation and chemotherapy works better at treating bladder cancer while allowing patients to keep their bladder instead of having it surgically removed.
Bladder cancer is often treated by removing the entire bladder, which significantly affects quality of life. This trial is exploring whether combining heat with radiation and chemotherapy can be just as effective while preserving the bladder and giving patients a better long-term outcome.
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You would receive deep regional hyperthermia (heating therapy) 1–2 times per week for up to 10 sessions, combined with radiation therapy delivered in multiple doses over several weeks. Some patients will also receive chemotherapy drugs given through an IV. The entire treatment course is designed to be completed on an outpatient basis, though the exact timeline and number of visits will depend on your individual treatment plan.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
Germany