Heating therapy combined with radiation for bladder cancer

This trial is testing a combination treatment for bladder cancer that uses deep regional hyperthermia (controlled heating of the bladder area) paired with radiation therapy and, for some patients, chemotherapy drugs including 5-Fluorouracil and Cisplatin. The goal is to see whether adding heat to radiation and chemotherapy works better at treating bladder cancer while allowing patients to keep their bladder instead of having it surgically removed.

Bladder cancer is often treated by removing the entire bladder, which significantly affects quality of life. This trial is exploring whether combining heat with radiation and chemotherapy can be just as effective while preserving the bladder and giving patients a better long-term outcome.