Plain-English translation of NCT05406232 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is observing how your immune system responds to radiation therapy for breast cancer. Researchers will collect small tissue samples from your tumor and blood samples at different time points to see how radiation affects your immune cells and causes changes in cancer cell DNA.
Doctors know that radiation therapy can trigger the immune system to fight cancer, but they don't fully understand exactly how this happens or how quickly it occurs. This research aims to map out these immune changes so that future treatments might be designed to work better with radiation.
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You will receive one radiation therapy session on day 1. Before that first treatment and then again on days 1, 3, and 7, you will undergo a small tissue punch biopsy of your tumor and have blood samples taken. The entire study participation spans about one week, during which you'll have four biopsy and blood collection visits.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Collaborators
Artidis
Enrollment target
~36 participants
Started
September 2023
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Simona F Shaitelman, MD
M.D. Anderson Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.