Plain-English translation of NCT05414409 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 1 Diabetes research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is investigating the role of gut bacteria in type 1 diabetes, especially in young people who are overweight or obese. Researchers will compare gut bacteria between teenagers with type 1 diabetes who are at a healthy weight and those who are overweight. Some participants will also take , a common medication used to help manage blood sugar, for 6 months while researchers study how it affects their gut bacteria and overall health.
More teenagers with type 1 diabetes are becoming overweight or obese, which makes managing their diabetes harder and increases their risk of serious complications. This trial aims to understand whether changes in gut bacteria play a role in this problem and whether this medication could help address it.
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If you join the comparison group, you will have your gut bacteria studied through blood and stool samples, and researchers will review your health information. If you are selected for the medication group, you will take by mouth for 6 months while researchers collect samples and monitor how the medication affects your gut bacteria and diabetes management. You'll have several study visits over the 6-month period.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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