Plain-English translation of NCT05417737 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study looking at ozone therapy as an additional treatment for people with chronic pain, nerve damage from cancer treatment, or delayed wound healing—especially when standard pain treatments haven't worked or cause serious side effects. Researchers want to see whether ozone therapy can improve your quality of life, reduce anxiety and depression, and help manage your pain symptoms.
Many patients have chronic pain that doesn't improve with conventional treatments, or those treatments cause unacceptable side effects or risks. This study exists to understand whether this treatment might help people when other options have failed or aren't safe enough.
You likely qualify if…
You likely don't qualify if…
You would receive ozone therapy sessions—usually about 40 sessions over approximately 16 weeks—at the hospital's Chronic Pain Unit. You would complete questionnaires about your quality of life, pain, anxiety, and depression at the start, after treatment ends, and at follow-up visits 12 and 24 weeks later. The study will follow you for a total of about 24 weeks after your treatment finishes.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
Spain
Sponsor
Bernardino Clavo, MD, PhD
Collaborators
Fundación Canaria Instituto de Investigación Sanitaria de Canarias, Servicio Canario de Salud
Enrollment target
~105 participants
Started
June 2022
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Bernardino Clavo, MD, PhyD
Dr. Negrín University Hospital, Las Palmas, Spain
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.