Plain-English translation of NCT05420454 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether albumin-bound paclitaxel (nab-paclitaxel) works better than when given before breast cancer surgery. Both are chemotherapy drugs designed to shrink tumors before operation. Researchers want to know which medication helps more patients achieve complete tumor response and has fewer side effects.
Previous studies suggest this medication may be more effective than the standard drug currently used, but doctors need a large, well-designed trial to confirm this and ensure it's truly the better choice for patients with different types of breast cancer.
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You will be randomly assigned to receive one of the two chemotherapy medications given through an IV before your planned breast cancer surgery. You'll visit the hospital regularly for treatment doses and blood tests to monitor your health and how well the medication is working. After completing the chemotherapy cycles, you will have surgery to remove the cancer, and the research team will follow your progress to see how completely the tumor responded to treatment.
AI-generated summary from trial data · Aug 11, 2026 · Not medical advice
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