Plain-English translation of NCT05421273 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial compares two different ways of delivering spinal cord stimulation—a type of implanted device that sends electrical pulses to help reduce pain. The study is testing whether an active recharge burst stimulation approach works better than a passive recharge burst approach for people with chronic spinal pain, particularly those who have not found relief from previous back surgery. Researchers want to see which method better reduces pain and improves quality of life.
Many people continue to experience severe chronic pain even after back surgery, and standard pain treatments don't always help enough. This trial exists to find out if one type of spinal cord stimulation might work better than another for reducing both the intensity of pain and the anxiety or catastrophic thinking that often goes with chronic pain.
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You will first go through a trial period with a temporary spinal cord stimulator to see if the treatment works for you. If successful, you'll receive a permanent implant and be randomly assigned to receive either active or passive recharge burst stimulation. Over the next 12 months, you'll visit the clinic multiple times (after your trial, then at 1, 3, 6, and 12 months after implantation) to complete questionnaires about your pain, mood, disability, and quality of life. The study is taking place across six hospitals in the Netherlands.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
Netherlands