Plain-English translation of NCT05424159 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a newer form of radiation therapy called carbon ion radiotherapy with pencil beam scanning for people with locally advanced pancreatic cancer that cannot be surgically removed. Unlike standard radiation, this treatment uses carbon ions—which are heavier particles—to target tumors more precisely. The goal is to see whether this treatment can control the cancer and whether it causes fewer side effects than traditional radiation.
Pancreatic cancer that cannot be surgically removed is very difficult to treat, and standard radiation therapy has limitations in how precisely it can target the tumor without harming nearby healthy tissue. This newer treatment approach may deliver radiation more accurately to the cancer while reducing damage to surrounding organs.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will receive carbon ion radiation therapy delivered over 3 weeks in 15 daily sessions. The treatment focuses on your pancreatic tumor, nearby lymph nodes, and areas at risk for cancer recurrence. Throughout the trial, you will have regular visits with your medical team that include physical exams, blood tests, and imaging scans (CT, MRI, or PET-CT) to monitor how well the treatment is working and to watch for any side effects.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
China
Sponsor
Shanghai Proton and Heavy Ion Center
Enrollment target
~48 participants
Started
July 2022
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in December 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Zheng Wang, MD, PhD
Shanghai Proton and Heavy Ion Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.