Plain-English translation of NCT05427058 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study compares two minimally invasive procedures—the superior hypogastric plexus block and the ganglion impar block—that target nerves in the lower spine and pelvis to relieve severe pain from cervical or endometrial cancer. Both procedures use lidocaine and alcohol injected with imaging guidance. The goal is to see which procedure works better and is safer for people whose pain is no longer controlled by oral pain medications.
Many patients with pelvic cancers experience severe pain that doesn't respond well to pain pills, and the medications themselves can cause difficult side effects like nausea and constipation. This trial aims to find out whether one of these two nerve-blocking procedures is more effective and safer than the other, giving doctors better options to help patients.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of the two nerve-blocking procedures. The procedure takes place in a clinic or hospital using imaging guidance (a special X-ray camera) to ensure accuracy. A pain specialist will inject medication around specific nerves in your lower spine or pelvis to block pain signals. You will then be monitored for safety and effectiveness, with follow-up visits to track how well the procedure is working for your pain relief.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Indonesia
Sponsor
University of Brawijaya
Enrollment target
~36 participants
Started
July 2024
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ristiawan M Laksono, MD,FIPP
Brawijaya University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.