Plain-English translation of NCT05428735 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether combining two different embolization procedures — blocking blood vessels to both the portal vein and hepatic vein — works better than blocking just the portal vein alone. Both approaches are designed to make your remaining healthy liver grow larger before you have surgery to remove cancer tumors, giving your liver enough function to stay healthy after the operation.
When colorectal cancer spreads to the liver, surgeons sometimes need to remove large portions of liver tissue to eliminate the cancer. Before doing this, doctors need to make sure you'll have enough healthy liver left to function properly after surgery. This trial is testing whether the newer combined approach grows your liver faster and more effectively than the current standard approach.
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You will be randomly assigned to receive one of the two procedures to help your liver grow. Both involve a minimally invasive intervention where doctors use imaging to guide catheters into blood vessels and block specific vessels to trigger liver growth. After the procedure, you'll have follow-up imaging and blood tests to monitor how well your liver is growing. Once your liver has grown enough, you'll return for surgery to remove the cancer tumors.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
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