Plain-English translation of NCT05429099 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether Virtual Surgical Planning (VSP)—a method that uses 3D computer models and printed surgical guides—leads to better outcomes than traditional free-hand surgery for patients who need jaw reconstruction due to oral cancer. Half of the participants will receive surgery planned with this new computer-assisted technology, while the other half will receive standard surgical care. Researchers will compare how well the jaw heals and functions in both groups over the first year after surgery.
When oral cancer invades the jawbone, surgeons must remove the affected bone and rebuild it using bone grafts. While early studies suggest that computer-assisted planning may improve healing and accuracy, no large-scale comparison has directly tested whether this newer approach is truly better than the traditional method that surgeons have used for many years.
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If you join this trial, you will be randomly assigned to receive either computer-assisted surgical planning or standard surgery. If assigned to the computer-planning group, a surgeon and engineer will work together using 3D models of your jaw to plan your surgery before the operation. You will then undergo jaw reconstruction surgery as planned. After surgery, you will have follow-up visits and a CT scan at 12 months to check how well your jaw has healed. You may also complete quality-of-life surveys and functional assessments throughout the year.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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