Plain-English translation of NCT05429632 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether , a new medication, can help prevent acute myeloid leukemia from coming back after you receive a blood cell transplant from a donor. You would take this medication by mouth once a day for 12 months while your body recovers from the transplant. The study compares two different doses of the medication against a placebo (a pill with no active ingredient) to see which works best and is safest.
Acute myeloid leukemia is a serious blood cancer, and even after a successful blood cell transplant, the disease can return. Researchers believe this medication might help prevent that relapse and improve survival, but they need to test it in a large, carefully controlled study to be sure it works and is safe.
You likely qualify if…
You likely don't qualify if…
You would take a daily oral medication (either the new treatment or placebo) for 12 months starting around the time of your blood cell transplant. You would visit the study clinic regularly for blood tests, examinations, and monitoring of side effects—especially in the months right after your transplant when you need close care anyway. The study involves about 366 participants across multiple hospitals, and neither you nor your doctors will know whether you're receiving the active medication or placebo until the study ends.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
United States