Plain-English translation of NCT05431101 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Carpal tunnel syndrome affects millions of people, causing pain, numbness, and weakness in the hand. Surgery is the most effective treatment, but some patients develop wound infections afterward. This trial compares two types of stitches—absorbable ones that dissolve on their own, and non-absorbable ones that must be removed—to find out which type results in fewer infections and better healing.
Doctors currently use both types of stitches in practice, but there isn't clear evidence about which one is safer or more effective. This study aims to settle that question by carefully tracking infection rates and wound healing in a large group of patients.
You likely qualify if…
You likely don't qualify if…
You will have carpal tunnel release surgery performed by your surgeon. During surgery, your wound will be closed with either absorbable or non-absorbable stitches, assigned randomly. After surgery, you'll be asked to track pain and healing for the first three weeks using a simple scoring system, and researchers will monitor your wound for any signs of infection during follow-up visits and with your hand therapist.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
Netherlands
Sponsor
Gelre Hospitals
Collaborators
Deventer Ziekenhuis
Enrollment target
~2,604 participants
Started
May 2022
Primary completion
March 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pauline Verhaegen, MD PHD
Gelre Hospitals
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.