Plain-English translation of NCT05434819 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Atrial Fibrillation research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether surgeons should perform a heart rhythm procedure called surgical ablation during heart surgery in patients who have atrial fibrillation (an irregular heartbeat). Half of the patients will receive the ablation procedure during their scheduled heart surgery, and half will not. The study will follow patients for 4 years to see if the procedure reduces future hospitalizations.
Atrial fibrillation affects millions of people and increases the risk of stroke and heart failure. Doctors want to know if fixing the irregular heartbeat during heart surgery—when the heart is already open—can prevent serious complications and improve patients' health outcomes.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be randomly assigned to either receive the ablation procedure during your scheduled heart surgery or not receive it. After surgery, you will visit the hospital for follow-up appointments at 4–6 weeks, 6 months, and then every 6 months for up to 4 years. During these visits, doctors will check your heart health and ask about any hospital stays or symptoms you've experienced.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
Canada
Sponsor
Population Health Research Institute
Collaborators
Hamilton Health Sciences Corporation
Enrollment target
~2,000 participants
Started
June 2023
Primary completion
September 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Richard Whitlock
Population Health Research Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.