Plain-English translation of NCT05438836 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Anal Cancer research guide →This trial is testing a new approach to radiation therapy for anal cancer called online adaptive radiotherapy. Instead of using the same radiation plan throughout your treatment, this new approach adjusts your radiation plan daily based on images taken right before each treatment. The goal is to reduce harmful side effects to your digestive system while still effectively treating the cancer.
Standard radiation therapy for anal cancer can cause significant digestive side effects early in treatment. This trial exists to see whether adjusting the radiation plan daily — based on how your body changes during treatment — can spare your digestive organs and reduce these uncomfortable side effects.
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If you join this trial, you will receive daily radiation therapy at the hospital. Before each treatment, doctors will take images to see how your body has changed since the last session, and they will adjust your radiation plan accordingly. This is a single-center trial at Herlev Hospital with a target of 205 participants, and the study is currently recruiting patients.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
Denmark
Enrollment target
~205 participants
Started
January 2022
Primary completion
January 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Eva Serup-Hansen, MD, PhD
Herlev og Gentofte Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.