Plain-English translation of NCT05439161 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is comparing two different surgical approaches for treating open angle glaucoma. You would receive either a XEN Glaucoma Gel Microstent implant—a newer, less invasive procedure—or a traditional trabeculectomy, which has been used successfully for over 50 years. Both are standard surgical treatments for glaucoma, and researchers want to understand which approach works better for preserving your vision.
Glaucoma surgery aims to lower eye pressure and prevent vision loss, but doctors want to know whether the newer, less invasive XEN implant works as well as the traditional trabeculectomy in protecting long-term vision. This trial will help answer that question.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will be randomly assigned to receive either the XEN implant surgery or the traditional trabeculectomy procedure. Before surgery, you'll have a baseline eye exam to establish your current vision and eye health. After surgery, you'll return for regular follow-up appointments at set intervals so doctors can measure your vision, check your eye pressure, and track how well the surgery is working. The study will involve visits at one of four European research centers in Austria.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Austria
Sponsor
Prof. Dr. Herbert Reitsamer
Enrollment target
~196 participants
Started
December 2023
Primary completion
March 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Markus Lenzhofer, MD PhD
Paracelsus Medical University Salzburg/ Salzburger Landeskliniken
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.