Plain-English translation of NCT05440617 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study invites people who are having their ovarian tissue frozen before cancer treatment (a procedure called ovarian tissue cryopreservation) to donate a portion of that tissue for research. Researchers will study the tissue to understand how healthy ovaries work and to track what happens to people's fertility in the years after cancer treatment.
Cancer treatments can damage or destroy a woman's eggs and ovaries, leading to infertility and early menopause. By collecting tissue samples and following participants over time, researchers hope to better understand the long-term effects of cancer therapy on fertility and improve ways to help patients have biological children after treatment.
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If you join, you'll have your ovarian tissue frozen as part of your regular cancer care. Researchers will use a small portion of that tissue for their studies. You'll also share your medical information and reproductive health outcomes in a national database over time, so scientists can track how cancer treatment affects fertility in the long term. There is no additional surgery or visits required beyond your standard cancer care.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United States
Enrollment target
~100 participants
Started
July 2022
Primary completion
September 2041
Age range
4 Years – 35 Years
Sex
Female only
Last updated on clinicaltrials.gov in June 2026.
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Central contact
Veronica Gomez-Lobo, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.