Plain-English translation of NCT05443555 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether , a medication used for nerve pain and other conditions, can help people with HIV who drink heavily to both reduce their alcohol use and get their viral load suppressed (meaning the virus becomes undetectable in their blood). The idea is that if the medication helps reduce drinking, people may be more able to take their HIV medications regularly and stay engaged with their care.
Many people with HIV struggle with heavy drinking, which makes it harder to stick with their HIV medications and keep their virus under control. Researchers want to see if this medication can help address both problems at once—reducing alcohol use while also helping people achieve better viral suppression.
If you join this study, you will be randomly assigned to receive either the active medication or a placebo (a dummy pill that looks identical) for 3 months. Everyone in the study will also receive a brief, evidence-based counseling conversation (about 5 minutes) focused on reducing alcohol use. You will need to visit the study site for appointments and complete the study procedures, and you should be prepared to commit to the full 3-month period.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
Uganda