Plain-English translation of NCT05444348 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new approach called ACT (Advance Consultations Concerning your Life and Treatment) designed to help patients with blood cancers like myeloma, lymphoma, and leukemia have meaningful conversations with their doctors and nurses about their values, goals, and end-of-life wishes. The goal is to help patients and families make informed decisions about treatment — including when to pursue aggressive therapy and when to focus on comfort and quality of life instead. If you join, you'll either receive the new ACT conversations or continue with standard care.
Many patients with blood cancers receive treatments near the end of life that don't help them feel better or live longer, and often experience unnecessary suffering. Doctors and nurses sometimes don't have good training in talking openly with patients about prognosis and what matters most to them, which can lead to treatments that don't match what patients truly want.
You likely qualify if…
You likely don't qualify if…
If your healthcare team is randomly selected for the ACT training, you and your caregiver will attend special planning conversations with your doctor or nurse that focus on your values, goals, and wishes for care. These conversations are designed to be compassionate and give you time to think through what matters most to you as you live with your cancer. You'll also complete some surveys about your experience and your quality of life. If your team is in the usual care group, you'll receive standard care and follow-up as normal.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
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