Plain-English translation of NCT05444478 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a combination approach for people with liver cancer that has returned after initial treatment. The study compares two groups: one receiving microwave ablation (a heat-based procedure that destroys cancer cells) alone, and another receiving the same procedure plus (a targeted medication that slows cancer growth). Researchers want to see if adding the medication to the procedure improves outcomes.
Microwave ablation has shown promise for early recurring liver cancer, and has been shown to help patients with advanced liver cancer. However, no one has studied whether combining these two treatments together works better than one alone, so this trial is needed to find out.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to receive either microwave ablation alone or microwave ablation combined with the targeted medication taken by mouth. The microwave ablation procedure is performed once to destroy your cancer cells using heat. If you are assigned to the combination group, you will also take the medication regularly as directed. You will have follow-up visits to monitor how you are responding to treatment and to check for any side effects.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
China
Sponsor
Sun Yat-sen University
Enrollment target
~274 participants
Started
July 2022
Primary completion
July 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in November 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Qunfnag Zhou, MD
Hunan Provincial People's Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.